Jesse will become fatally ill but he has exorbitant amounts of money to offer anyone who can treat him. Anyone want the job? He'll be cared for by Lisbeth and Walt (if Walt's app is accepted by then, that is).

Shikamaru will spend his time trying to develop a treatment (since he's an herbalist - little known fact). He actually won't get all that sick; he's made some spiritual progress this year. Open to collaboration with any other people working on a cure?